Passwater: You have taken an interest in Pycnogenol for heart health both in your cardiac remodeling study and your most recent work on Pycnogenol reducing symptoms of cardiovascular risk factors in diabetics. Please elaborate on the findings.
Watson: Initially, I began to study the heart health benefits of Pycnogenol. The majority of the beneficial effects of Pycnogenol for heart health are likely related to the enhanced generation of nitric oxide in cells lining blood vessel walls. The nitric oxide relieves arterial constriction and this releases the pressure build-up in the vascular system. At the same time, nitric oxide renders blood platelets less sticky, somewhat like the body’s own aspirin, which helps prevent thrombotic events. We were the first researchers pointing to anti-inflammatory activities of Pycnogenol in humans. We showed this effect for the first time in students who took Pycnogenol tablets, which protected them from getting sunburn under controlled exposure to UV light in the lab.